Description

Z,Z-Dienestrol-D6 is a deuterium-labeled analog of the synthetic estrogen dienestrol, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS/MS) analyses. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in method development, pharmacokinetic studies, and residue analysis.

Application

• Internal Standard for Bioanalytical Assays: Essential for the precise quantification of dienestrol and related compounds in complex biological matrices such as plasma, serum, and tissue homogenates.
• Pharmaceutical Research & Development: Used in method validation, stability testing, and metabolism studies during drug development processes.
• Veterinary Drug Residue Analysis: Applied in food safety testing to monitor for unauthorized or excessive use of hormonal substances in livestock.
• Environmental Monitoring: Supports the detection and quantification of estrogenic compounds in environmental water samples and effluents.
• Clinical Toxicology: Aids in the accurate measurement of hormone levels for diagnostic and forensic investigations.
• Quality Control in Reference Material Production: Serves as a critical component in the preparation and certification of certified reference materials (CRMs).

Basic Information

Product Name	Z,Z-Dienestrol-D6
CAS No.	91297-99-3
Molecular Formula	C18H14D6O2
Molecular Weight	274.38 g/mol
Synonyms	Dienestrol-d6; (E,E)-4,4'-(1,2-Diethylidene-1,2-ethanediyl)bisphenol-d6; 3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene-d6; Hexadienestrol-d6; Dienoestrol-d6; NSC-3070-d6; Dehydrostilbestrol-d6
EINECS	Contact for details

Quality Control

Every batch of Z,Z-Dienestrol-D6 is manufactured and analyzed under strict quality systems to ensure the highest standards of isotopic purity and chemical identity, which are paramount for its function as an analytical standard. We provide comprehensive Certificates of Analysis (COA) detailing results for isotopic enrichment (D6), chemical purity (by HPLC), and identity confirmation (by NMR and MS). Our quality commitment aligns with the needs of GMP/GLP-compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D6)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.