Description

Apitoxin, also known as bee venom, is a complex natural product with the CAS registry number 91261-16-4. This potent bioactive substance is valued for its unique composition of peptides, enzymes, and amines, which confer significant pharmacological and therapeutic potential. It is primarily sought after by the pharmaceutical, cosmetic, and biomedical research industries for applications ranging from anti-inflammatory therapeutics to advanced dermatological formulations.

Application

• Pharmaceutical Research & Development: Used as a key active ingredient in studies for anti-arthritic, anti-inflammatory, and neuroprotective drug candidates.
• Cosmeceutical Formulations: Incorporated into anti-aging and skin-rejuvenating products for its purported collagen-stimulating and anti-wrinkle effects.
• Apitherapy & Alternative Medicine: Serves as the primary agent in controlled apitherapy treatments for chronic pain and autoimmune condition management.
• Biochemical & Neuroscience Research: Utilized as a research tool to study ion channel function (e.g., melittin's effect on membranes) and neural signaling pathways.
• Immunology Studies: Employed in the development of desensitization protocols and the study of allergic responses due to its immunogenic components.
• Veterinary Medicine: Explored for use in topical ointments and treatments for animal musculoskeletal conditions.

Basic Information

Product Name	Apitoxin
CAS No.	91261-16-4
Molecular Formula	Complex mixture
Molecular Weight	N/A (Mixture)
Synonyms	Bee Venom; Apis Venom; Apitoxine; BV (Bee Venom); Honey Bee Venom; Apis mellifera Venom; Melittin (major component); Apamin (component); Phospholipase A2 (component); Hyaluronidase (component)
EINECS	Contact for details

Quality Control

Our Apitoxin is sourced and processed under stringent controls to ensure batch-to-batch consistency and biological activity. Quality is verified through a series of analytical methods including HPLC for peptide profiling, activity assays for key enzymes like phospholipase A2, and tests for sterility and endotoxin levels where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, composition, and biological potency is provided with each shipment to support your research and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to light yellow lyophilized powder
Identification (HPLC)	Conforms to standard profile
Protein Content (Biuret)	≥ 85%
Melittin Content (HPLC)	40 - 55%
Phospholipase A2 Activity	≥ 100 units/mg
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 2.0%
Microbial Limits	Meets specified criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.