Description

2-Hydroxypropylvaline is a specialized amino acid derivative with a branched-chain structure, offering unique chemical functionality for advanced synthesis. This compound is valued for its role as a key chiral building block and intermediate in the development of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring high-purity, custom-tailored intermediates.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Peptide Synthesis: Used as a modified amino acid residue in the production of custom peptides and peptidomimetics for biochemical research and therapeutic development.
• Agrochemical Research: Acts as a building block for creating advanced crop protection agents and herbicides with specific stereochemical properties.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Bioconjugation & Linker Chemistry: Utilized in the design of drug conjugates, antibody-drug linkers, and other bioconjugation strategies due to its reactive hydroxyl and carboxyl groups.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Hydroxypropylvaline
CAS No.	91147-54-5
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	2-Hydroxy-3-methylbutanoic acid, 1-aminoethyl-; L-Valine, N-(1-hydroxy-2-propyl)-; (2S)-2-Amino-3-methylbutanoic acid 1-(2-hydroxypropyl) ester; N-(2-Hydroxypropyl)valine; Valine, N-(2-hydroxypropyl)-; 2-Hydroxypropyl-L-valine; α-Aminoisovaleric acid 2-hydroxypropyl ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxypropylvaline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality frameworks for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.