Description

Boc-L-Vinylglycine is a protected, non-proteinogenic amino acid derivative of significant value in synthetic organic chemistry and pharmaceutical research. Its primary importance lies in its role as a versatile chiral building block for the synthesis of complex peptides and biologically active compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors, particularly for developing novel enzyme inhibitors and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly enzyme inhibitors and peptide mimetics.
• Peptide Chemistry Research: Used to incorporate the unique vinylglycine moiety into peptide chains to study conformational effects and biological activity.
• Protease Inhibitor Development: Serves as a crucial precursor for creating irreversible or mechanism-based inhibitors of various proteolytic enzymes.
• Agrochemical Synthesis: Employed in the research and development of advanced, bioactive compounds for crop protection.
• Biochemical Tool Compound: Utilized in biochemical assays to investigate amino acid metabolism and enzyme mechanisms.
• Academic & Industrial R&D: A valuable reagent for organic synthesis methodologies and exploring new chemical entities in discovery chemistry.

Basic Information

Product Name	Boc-L-Vinylglycine
CAS No.	91028-39-6
Molecular Formula	C₉H₁₅NO₄
Molecular Weight	201.22 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]pent-4-enoic acid; N-(tert-Butoxycarbonyl)-L-vinylglycine; N-Boc-L-vinylglycine; Boc-Vinylglycine-OH; L-Vinylglycine, N-Boc-; BOC-L-2-AMINO-4-PENTENOIC ACID; tert-Butyl (1S)-1-carboxy-3-buten-1-ylcarbamate
EINECS	Contact for details

Quality Control

Our Boc-L-Vinylglycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.