Description

Tedisamil is a selective potassium channel blocker with significant pharmacological activity. This compound is a valuable research chemical and pharmaceutical intermediate, primarily utilized in the development and study of antiarrhythmic and cardioprotective agents. It is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those focused on cardiovascular drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced antiarrhythmic drug candidates.
• Cardiovascular Research: Used as a reference standard and active compound in preclinical studies investigating myocardial ischemia and arrhythmia mechanisms.
• Biochemical Research: Employed as a selective tool to study the role and function of specific potassium channels (IKr) in cellular electrophysiology.
• API Development: Serves as a core structure for the development of novel Active Pharmaceutical Ingredients (APIs) targeting cardiac conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Tedisamil
CAS No.	90961-53-8
Molecular Formula	C18H28N2O2S
Molecular Weight	336.49 g/mol
Synonyms	KC 8857; Tedisamil dihydrochloride (salt form); 1,3-Bis(2,6-dimethylphenoxy)-2-propanamine; trans-1,3-Bis(2,6-dimethylphenoxy)-2-propylamine; trans-N-[3-(2,6-Dimethylphenoxy)-2-hydroxypropyl]-2,6-dimethylaniline; (1R,2S)-rel-1,3-Bis(2,6-dimethylphenoxy)-2-propanamine
EINECS	Contact for details

Quality Control

Our Tedisamil is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.