Description

(17R,21-Alpha)-17,21-Dihydroxy-4-(2-Propenyl)Ajmalanium Bromide is a high-purity, semi-synthetic ajmaline derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are critical for developing targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiovascular and antiarrhythmic drugs, as well as in specialized organic chemistry research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex, biologically active molecules, particularly for cardiovascular applications.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in pharmacological studies to investigate ion channel modulation and related biological pathways.
• Fine Chemical Synthesis: Serves as a specialized precursor for the preparation of other ajmaline-based analogs and derivatives.

Basic Information

Product Name	(17R,21-Alpha)-17,21-Dihydroxy-4-(2-Propenyl)Ajmalanium Bromide
CAS No.	107870-71-3
Molecular Formula	C22H29N2O2Br
Molecular Weight	433.39 g/mol
Synonyms	4-Allylajmaline Bromide; 17,21-Dihydroxy-4-(2-propen-1-yl)ajmalanium Bromide; 4-Allylajmalinium Bromide; Ajmaline, 4-allyl-, bromide; (17R,21α)-17,21-Dihydroxy-4-(2-propen-1-yl)ajmalanium Bromide; 4-(2-Propenyl)ajmalanium Bromide; 4-Allylajmaline Quaternary Salt
EINECS	Contact for details

Quality Control

Our (17R,21-Alpha)-17,21-Dihydroxy-4-(2-Propenyl)Ajmalanium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.