Description

Amiodarone CAS NO 1951-25-3 is a potent class III antiarrhythmic agent, a benzofuran derivative widely recognized for its efficacy in managing severe cardiac rhythm disorders. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the safety and therapeutic consistency of life-saving cardiovascular medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiarrhythmic drug formulations, including tablets and injectables.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antiarrhythmic medications for treating ventricular tachycardia and fibrillation.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Research & Development: Key compound in preclinical and clinical studies for cardiovascular drug discovery and pharmacology.
• Formulation Development: Serves in the development of various dosage forms, including oral tablets and intravenous injections.
• Generic Drug Manufacturing: Essential for producing bioequivalent generic versions of branded antiarrhythmic drugs.

Basic Information

Product Name	Amiodarone
CAS No.	1951-25-3
Molecular Formula	C25H29I2NO3
Molecular Weight	681.31 g/mol
Synonyms	Amiodarone Hydrochloride (common salt form); Cordarone; Atlansil; Aratac; 2-Butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone; (2-Butyl-1-benzofuran-3-yl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone; SKF-33134-A
EINECS	217-793-8

Quality Control

Our Amiodarone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards such as USP and EP. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.