Description

Variolysin CAS NO 90882-02-3 is a highly specific and potent proteolytic enzyme derived from microbial fermentation. This product matters for its critical role in biopharmaceutical manufacturing and life science research, where precise protein cleavage is required. It is primarily needed by the pharmaceutical industry for downstream processing, including viral inactivation and vaccine purification, as well as by research laboratories for protein analysis and structural studies.

Application

• Viral Vaccine Production: Used for the controlled cleavage and inactivation of viral particles in the manufacturing of vaccines.
• Biopharmaceutical Downstream Processing: Employed in purification processes to remove host cell proteins and other process-related impurities.
• Protein Research & Analysis: A valuable tool in laboratories for protein sequencing, peptide mapping, and structural biology studies.
• Cell Culture Applications: Facilitates the detachment of adherent cells in bioprocessing workflows.
• Diagnostic Reagent Formulation: Incorporated into diagnostic kits and assays that require specific enzymatic activity.

Basic Information

Product Name	Variolysin
CAS No.	90882-02-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VCP; Variola virus complement control protein; Smallpox inhibitor of complement enzymes (SPICE); Variola virus protease; EC 3.4.21.97; Complement regulatory protein; Serine protease Variolysin
EINECS	Contact for details

Quality Control

Our Variolysin is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including activity assays and purity profiling, to meet the exacting standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, activity, and other critical parameters is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference standard
Assay (Enzymatic Activity)	≥ 95%
Protein Content (Biuret)	≥ 90%
Purity (SDS-PAGE)	≥ 90%
Endotoxin (LAL)	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.