Description

Parathyroid Hormone Fragment (Asn76)- CAS NO 90880-43-6 is a specific, biologically active peptide fragment derived from the parathyroid hormone (PTH) sequence. This compound is critical for research into calcium and phosphate metabolism, bone physiology, and renal function. It serves as a valuable tool for scientists and developers in the pharmaceutical, biotechnology, and academic research sectors, particularly for assay development, receptor binding studies, and metabolic disorder research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of parathyroid hormone receptor (PTH1R) signaling and function.
• Pharmaceutical Development: Employed in the screening and development of novel therapeutics targeting bone diseases such as osteoporosis and hyperparathyroidism.
• Diagnostic Assays: Serves as a critical component in the calibration and validation of immunoassays (e.g., ELISA) designed to measure PTH-related peptides.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of PTH fragments on osteoblast and osteoclast activity.
• Metabolic Disorder Research: A key reagent for exploring the pathophysiology of disorders related to calcium homeostasis.
• Peptide Chemistry & Conjugation: Used as a starting material or intermediate for the synthesis of labeled peptides (e.g., fluorescent, radioactive) for advanced research applications.

Basic Information

Item	Detail
Product Name	Parathyroid Hormone Fragment (Asn76)- CAS NO 90880-43-6
CAS No.	90880-43-6
Molecular Formula	C181H291N55O51S2
Molecular Weight	4107.7 g/mol
Synonyms	Parathyroid Hormone (1-34) amide, human; PTH (1-34), human; Teriparatide acetate (fragment); hPTH(1-34)NH2; Parathyroid hormone fragment 1-34 amide; [Asn76]-Parathyroid Hormone (1-84) (human) fragment; PTH 1-34 amide, human recombinant; UNII-10T9CSU1I9 (acetate)
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone Fragment (Asn76) is manufactured and tested under strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, MS, and amino acid analysis to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 15.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.