Description

(S)-A-Bromo-A-(4-Methyl Phenyl)-Acetonitril is a high-value chiral building block and synthetic intermediate essential for asymmetric synthesis. Its primary commercial value lies in its utility for constructing complex, optically active molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is critical for research chemists and process development scientists in fine chemical and active pharmaceutical ingredient (API) manufacturing who require high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), especially those containing a benzylic stereocenter.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides, herbicides, and fungicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and for exploring new asymmetric synthetic routes.

Basic Information

Product Name	(S)-A-Bromo-A-(4-Methyl Phenyl)-Acetonitril
CAS No.	90775-10-3
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	(S)-α-Bromo-p-tolylacetonitrile; (S)-(-)-α-Bromo-4-methylbenzyl cyanide; (S)-2-Bromo-2-(4-methylphenyl)acetonitrile; (S)-Bromo(4-methylphenyl)acetonitrile; (S)-p-Tolyl bromoacetonitrile; (S)-1-Bromo-1-(4-methylphenyl)methane nitrile; (S)-Bromo(4-tolyl)acetonitrile; (S)-α-Bromo-4-methylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our (S)-A-Bromo-A-(4-Methyl Phenyl)-Acetonitril is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored in a desiccated environment away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.