Description

2-Bromo-1-Ethynyl-4,5-Dimethoxy-Benzene is a versatile and highly functionalized aromatic building block featuring both bromo and ethynyl substituents. This compound is critical for advanced organic synthesis, enabling efficient cross-coupling reactions and serving as a key precursor for complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) via Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require the ethynyl-benzene core structure.
• Material Science Research: Serves as a monomer or precursor for conjugated polymers, organic semiconductors, and liquid crystals due to its rigid, electron-rich aromatic system.
• Chemical Biology & Probe Development: Employed in click chemistry applications to create fluorescent tags, bioconjugates, and molecular probes for diagnostic and research purposes.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Bromo-1-Ethynyl-4,5-Dimethoxy-Benzene
CAS No.	90772-55-7
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	2-Bromo-1-ethynyl-4,5-dimethoxybenzene; 4,5-Dimethoxy-2-bromoethynylbenzene; 1-Bromo-2-ethynyl-4,5-dimethoxybenzene; 2-Bromo-4,5-dimethoxyphenylacetylene; 2-Ethynyl-4,5-dimethoxybromobenzene; Veratrole, 2-bromo-1-ethynyl-; (2-Bromo-4,5-dimethoxyphenyl)acetylene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Ethynyl-4,5-Dimethoxy-Benzene is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.