Description

7Beta-(2-(2-Aminothiazol-4-Yl)-2-Methoxyiminoacetamido)-3-Methyl-3-Cephem-4-Carboxylic Acid Glycylaminobenzoyloxymethyl Ester is a key advanced pharmaceutical intermediate in the synthesis of modern cephalosporin antibiotics. Its value lies in its role as a critical building block for constructing potent, broad-spectrum antibacterial agents with enhanced stability against β-lactamases. This compound is essential for pharmaceutical manufacturers and R&D laboratories focused on developing and producing next-generation antibiotic therapies.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary use as a crucial intermediate in the chemical synthesis of advanced-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Serves as a key scaffold for medicinal chemists exploring new antibacterial compounds and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Used in the development and optimization of commercial-scale manufacturing processes for cephalosporin drugs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of finished antibiotic products.
• Antibacterial Agent Precursor: The core structure is designed to yield final drug molecules effective against a wide range of Gram-positive and Gram-negative bacteria.

Basic Information

Product Name	7Beta-(2-(2-Aminothiazol-4-Yl)-2-Methoxyiminoacetamido)-3-Methyl-3-Cephem-4-Carboxylic Acid Glycylaminobenzoyloxymethyl Ester
CAS No.	90712-47-3
Molecular Formula	C22H23N7O7S2
Molecular Weight	561.59 g/mol
Synonyms	(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Glycylaminobenzoyloxymethyl Ester; Cephalosporin C-7 Glycyl Ester Intermediate; 7-ATMA-Gly Ester; Aminothiazolyl Methoxyimino Cephem Ester; Cefotaxime Related Compound Ester; Cephalosporin Synthon; Antibiotic Intermediate 90712-47-3
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.