Description

(2-Amino-5,6-Dimethylbenzimidazolyl)Cobamide is a specialized, high-purity cobalamin (vitamin B12) derivative, distinguished by its unique benzimidazole-based axial ligand. This compound is critical for advanced biochemical research and pharmaceutical development where precise molecular structure and biological activity are paramount. It is primarily utilized by research institutions, diagnostic manufacturers, and fine chemical producers in the life sciences sector.

Application

• Biochemical Research: As a reference standard and key intermediate in the study of cobalamin-dependent enzymes and metabolic pathways.
• Pharmaceutical Synthesis: Serves as a crucial precursor in the development of novel vitamin B12 analogs and targeted therapeutics.
• Diagnostic Reagents: Used in the formulation of high-sensitivity immunoassays and clinical diagnostic kits for vitamin B12 deficiency.
• Cell Culture & Microbiology: An essential growth factor in specialized cell culture media and for cultivating certain microorganisms.
• Nutritional Science: Employed in research focused on advanced nutrient delivery systems and bioavailability studies.
• Analytical Standard: Provides a certified reference material for HPLC, LC-MS, and other analytical methods in quality control laboratories.

Basic Information

Product Name	(2-Amino-5,6-Dimethylbenzimidazolyl)Cobamide
CAS No.	90654-06-1
Molecular Formula	C72H100CoN18O17P
Molecular Weight	~1579.6 g/mol
Synonyms	Vitamin B12 Derivative; Cobamide, (2-amino-5,6-dimethyl-1H-benzimidazol-1-yl)-; 5,6-Dimethylbenzimidazolylcobamide; Coα-[α-(5,6-Dimethylbenzimidazolyl)]-Coβ-cyanocobamide; B12 Vitamin Analog; Cyanocobalamin Analog; Cobalamin Precursor; 2-Amino-5,6-dimethylbenzimidazole cobamide
EINECS	Contact for details

Quality Control

Our (2-Amino-5,6-Dimethylbenzimidazolyl)Cobamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (UV-Vis, IR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or moisture should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Dark red crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.