Description

(S)-n-Boc-Allylglycine CAS NO 90600-20-7 is a high-purity, non-proteinogenic amino acid derivative featuring a Boc-protected amine and an allyl side chain. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, enabling the introduction of unique structural motifs and enabling further functionalization via the allyl group. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the unique (S)-allylglycine residue into peptide chains.
• Medicinal Chemistry Research: Serves as a versatile building block for creating focused libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Bioconjugation & Probe Development: The allyl group provides a handle for click chemistry or other modification strategies to create labeled peptides or bioconjugates.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring protected amino acid components.
• Academic & Institutional Research: Used in biochemical and chemical research for studying enzyme mechanisms, protein engineering, and developing new synthetic methodologies.

Basic Information

Product Name	(S)-n-Boc-Allylglycine
CAS No.	90600-20-7
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid; (S)-2-(tert-Butoxycarbonylamino)-4-pentenoic acid; Boc-L-Allylglycine; Boc-(S)-Allylglycine; (S)-Boc-Allylglycine; (S)-2-(Boc-amino)-4-pentenoic acid; L-Boc-Allylglycine; N-Boc-L-allylglycine
EINECS	Contact for details

Quality Control

Our (S)-n-Boc-Allylglycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity by HPLC, and residual solvent content. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (ee)	≥99.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.