Description

5-(4-Fluorophenyl)Pyrrolidin-2-One is a high-purity fluorinated heterocyclic compound, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its value lies in the unique structural motif combining a pyrrolidinone core with a fluorinated aromatic ring, enabling precise modifications in drug discovery and material science. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorophenyl group enhances biological activity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in the manufacture of high-performance display technologies.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes, including cross-coupling reactions.
• Academic & Contract Research: Serves as a standard reagent for methodological studies in fluorination chemistry and heterocycle synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fluorinated molecules for various high-value industrial applications.

Basic Information

Product Name	5-(4-Fluorophenyl)Pyrrolidin-2-One
CAS No.	90432-58-9
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	5-(4-Fluorophenyl)-2-pyrrolidinone; 5-(p-Fluorophenyl)-2-pyrrolidinone; 2-Pyrrolidinone, 5-(4-fluorophenyl)-; 5-(4-Fluorophenyl)-2-pyrrolidone; 5-(4-Fluorophenyl)dihydro-2(3H)-furanone; 90432-58-9; 5-(4-Fluorophenyl)pyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.