Description

7-Xylosyl-10-Deacetyltaxol is a key semi-synthetic intermediate in the production of paclitaxel, a potent and widely used chemotherapeutic agent. This compound is critical for pharmaceutical manufacturers seeking to develop and scale up efficient synthesis pathways for complex taxane derivatives. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug development, process chemistry, and the production of high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step semi-synthesis of Paclitaxel (Taxol®) and related anti-cancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) of taxane analogs.
• Process Development: Serves as a reference standard and starting material for optimizing synthetic routes in API manufacturing.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for quality control and impurity profiling of taxane-based pharmaceuticals.
• Precursor for Derivatives: Used in the synthesis of novel taxoid derivatives with potential for improved efficacy or reduced side effects.

Basic Information

Product Name	7-Xylosyl-10-Deacetyltaxol
CAS No.	90332-63-1
Molecular Formula	C45H51NO15
Molecular Weight	845.89 g/mol
Synonyms	10-Deacetyl-7-xylosyltaxol; 7-Xylosyltaxol B; 7-(Xylosyl)taxol; 10-Deacetyl-7-epitaxol; 7-Xylosylpaclitaxel; Taxol derivative 7-xylosyl; 7-O-Xylosyl-10-deacetyltaxol; NSC 654663
EINECS	Contact for details

Quality Control

Our 7-Xylosyl-10-Deacetyltaxol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. For long-term storage, consider storing at -20°C under inert atmosphere. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.