Description

4-Amino-n-1-Azabicyclo[2.2.2]Oct-3-Yl-5-Chloro-2-Methoxybenzamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those with neurological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and novel compound discovery.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	4-Amino-n-1-Azabicyclo[2.2.2]Oct-3-Yl-5-Chloro-2-Methoxybenzamide Hydrochloride
CAS No.	90182-92-6
Molecular Formula	C15H21ClN4O2 • HCl
Molecular Weight	369.72 g/mol (Free base: 333.81 g/mol)
Synonyms	5-Chloro-2-methoxy-4-[(3-quinuclidinyl)amino]benzamide Hydrochloride; 4-Amino-5-chloro-2-methoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide Hydrochloride; Quinuclidinyl Benzamide Derivative; 3-Aminoquinuclidine Benzamide Hydrochloride; CAS 90182-92-6; UNII-9K7J5JZ22B; 4-Amino-5-chloro-2-methoxy-N-(2-azabicyclo[2.2.2]octan-3-yl)benzamide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-n-1-Azabicyclo[2.2.2]Oct-3-Yl-5-Chloro-2-Methoxybenzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.