Description

Atrial Natriuretic Peptide (126-150) (Rat) is a defined synthetic peptide fragment corresponding to a specific region of the rat ANP hormone. This high-purity peptide is critical for cardiovascular and renal research, serving as a precise biochemical tool for studying natriuretic peptide receptor binding, signal transduction pathways, and physiological mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on hypertension, heart failure, and renal function studies.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of natriuretic peptide systems.
• Receptor Binding Assays: Essential for competitive binding studies to characterize and quantify ANP receptors (NPR-A).
• Signal Transduction Studies: Investigates the activation of guanylyl cyclase and downstream cGMP-mediated pathways.
• Pharmaceutical Screening: Serves as a control compound in high-throughput screening for novel cardiovascular drug candidates.
• Antibody Production & Immunoassays: Acts as an immunogen for antibody generation or as a calibrator in ELISA and RIA development.
• Cell Culture & Physiology: Applied in vitro to study effects on vascular tone, renal sodium excretion, and cellular proliferation.

Basic Information

Product Name	Atrial Natriuretic Peptide (126-150) (Rat)
CAS No.	90052-57-6
Molecular Formula	C124H204N40O39S2
Molecular Weight	2847.3 g/mol
Synonyms	ANP (126-150), rat; Atriopeptin (126-150); Cardionatrin (126-150); rANP(126-150); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23); Atrial Natriuretic Factor fragment 126-150
EINECS	Contact for details

Quality Control

Every batch of Atrial Natriuretic Peptide (126-150) (Rat) is manufactured and analyzed under strict quality systems. Identity, purity, and composition are verified using advanced analytical techniques including HPLC and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.