Description

Nicotinamide, 1-(2-Chloroethyl)-1,4-Dihydro- is a specialized nicotinamide derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in its unique molecular structure, which incorporates a reactive chloroethyl group onto the dihydropyridine ring, making it a versatile building block for medicinal chemistry research and development. This compound is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing novel therapeutic agents, particularly in areas such as enzyme inhibitors and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nicotinamide-based drug candidates and enzyme inhibitors.
• Medicinal Chemistry Research: Serves as a key building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Probe Development: Used in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation during early-stage drug development.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and chemical biology projects.

Basic Information

Product Name	Nicotinamide, 1-(2-Chloroethyl)-1,4-Dihydro-
CAS No.	90002-89-4
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	1-(2-Chloroethyl)-1,4-dihydronicotinamide; 1,4-Dihydro-1-(2-chloroethyl)nicotinamide; 3-Pyridinecarboxamide, 1-(2-chloroethyl)-1,4-dihydro-; N-(2-Chloroethyl)-1,4-dihydronicotinamide; 1-(2-Chloroethyl)-1,4-dihydro-3-pyridinecarboxamide; 1,4-DHP derivative; Chloroethyl DHP Nicotinamide
EINECS	Contact for details

Quality Control

Our Nicotinamide, 1-(2-Chloroethyl)-1,4-Dihydro- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.