Description

Haptoglobin, Human is a plasma glycoprotein that binds free hemoglobin with high affinity, preventing iron loss and renal damage. This product is essential for research and diagnostic applications requiring a high-purity, biologically active human protein. It is primarily utilized by biotechnology firms, clinical research organizations, and diagnostic kit manufacturers for applications in immunology, hematology, and biomarker studies.

Application

• Diagnostic Reagent Manufacturing: A key component in immunoassays and kits for the quantitative measurement of haptoglobin levels in human serum, aiding in the diagnosis of hemolytic anemias and inflammatory conditions.
• Biochemical Research: Used as a standard or reagent in studies investigating hemoglobin clearance, oxidative stress, and acute phase inflammatory responses.
• Cell Culture & Immunology: Employed in specialized cell culture media and immunological studies to understand its role in modulating immune function and protecting against hemoglobin-driven toxicity.
• Reference Standard: Serves as a purified reference material for quality control and calibration in clinical laboratory settings and pharmaceutical development.
• Protein-Protein Interaction Studies: Utilized in research to characterize the binding kinetics and complex formation between haptoglobin and hemoglobin or other ligands.

Basic Information

Product Name	Haptoglobin, Human
CAS No.	9087-69-8
Molecular Formula	Contact for details
Molecular Weight	~86-100 kDa (glycosylated tetramer)
Synonyms	Haptoglobin; Hp; Hemoglobin-binding Protein; α-2-Sialoglycoprotein; HPT; HP; Zonulin; Haptoglobin Complex; Hemoglobin Haptoglobin Complex; Acute Phase Protein
EINECS	Contact for details

Quality Control

Our Haptoglobin, Human is produced and tested under stringent quality management systems. Each lot is characterized for identity, purity, and biological activity to ensure consistency and reliability for critical research and diagnostic applications. Certificates of Analysis (COA) detailing purity (by HPLC/SDS-PAGE), functional activity, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (Immunological)	Complies
Purity (SDS-PAGE)	≥ 95%
Assay (Functional)	≥ 90% of labeled activity
Endotoxin	< 1.0 EU/mg
Solubility	Soluble in water or buffered saline

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.