Description

Prethrombins CAS NO 9070-19-3 is a high-purity biochemical reagent, a complex of prothrombin and other vitamin K-dependent clotting factors. This product is critical for research and development in the fields of hemostasis and thrombosis, serving as a key intermediate or substrate in coagulation studies. It is essential for pharmaceutical companies, diagnostic kit manufacturers, and advanced life science research institutions focused on blood coagulation pathways, anticoagulant drug discovery, and clinical diagnostics.

Application

• Coagulation Research: Used as a fundamental substrate for studying the intrinsic and extrinsic pathways of blood clotting.
• Diagnostic Reagent Production: A key component in the manufacturing of test kits for prothrombin time (PT) and activated partial thromboplastin time (aPTT) assays.
• Pharmaceutical Development: Employed in the screening and potency testing of novel anticoagulant and procoagulant therapeutics.
• Enzyme Kinetics Studies: Serves as a precursor for thrombin generation in studies of serine protease kinetics and inhibitor mechanisms.
• Quality Control in Biologics: Used as a reference standard in the quality control of plasma-derived products and recombinant clotting factors.
• Biochemical Standardization: Acts as a calibrator or control material in clinical laboratories to ensure the accuracy of coagulation analyzers.

Basic Information

Product Name	Prethrombins
CAS No.	9070-19-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Prothrombin Complex; Factor II; Coagulation Factor II; Prethrombin; Thrombogen; Prothrombin (Factor II) Precursor; Autoprothrombin I; Blood Coagulation Factor II; Thrombin Precursor
EINECS	Contact for details

Quality Control

Our Prethrombins are manufactured and tested under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional activity. Specifications are aligned with research-grade standards, and a comprehensive Certificate of Analysis (COA) detailing assay results, purity by HPLC, and biological activity is provided with every shipment to guarantee batch-to-batch consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or inert atmosphere to maintain stability. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (IR)	Conforms to reference standard
Assay (Functional Activity)	≥ 90% (by chromogenic substrate assay)
Purity (HPLC)	≥ 95%
Moisture Content (KF)	≤ 5.0%
Solubility	Clear, colorless solution in specified buffer
Biological Activity	Specific activity provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.