Description

Hemoglobin Bethesda is a specific variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for advanced research and diagnostic applications requiring precise and consistent protein behavior. It is primarily utilized by biotechnology firms, clinical diagnostic manufacturers, and academic research institutions investigating hematological disorders and oxygen transport mechanisms.

Application

• Biochemical Research: Used as a standard or model protein in studies of hemoglobinopathy, oxygen affinity, and protein stability.
• Diagnostic Reagent Manufacturing: Serves as a key component in the calibration and production of in-vitro diagnostic (IVD) kits for blood disorder testing.
• Hematology Reference Material: Acts as a controlled substance for quality control and assay validation in clinical laboratories.
• Pharmaceutical Development: Employed in early-stage research for potential therapeutic agents targeting sickle cell disease and other hemoglobin-related conditions.
• Educational & Training Kits: Incorporated into laboratory teaching materials for university-level biochemistry and medical technology courses.

Basic Information

Product Name	Hemoglobin Bethesda
CAS No.	9066-21-1
Molecular Formula	Contact for details
Molecular Weight	~64,500 g/mol (for tetramer)
Synonyms	Hb Bethesda; Hemoglobin β145 Tyr→His; Hemoglobin Rainier; High Oxygen Affinity Hemoglobin Bethesda; Unstable Hemoglobin Bethesda; HBB p.Tyr145His; Bethesda Hemoglobin Variant
EINECS	Contact for details

Quality Control

Our Hemoglobin Bethesda is produced and handled under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional consistency. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), spectral identification, and physical characteristics is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (UV-Vis)	Conforms to standard spectrum
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Moisture Content (KF)	≤ 5.0%
Solubility	Clear solution in buffer
Biological Activity (O2 affinity)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.