Description

Oxyhemoglobin A CAS NO 9062-91-3 is a purified, oxygenated form of the major adult hemoglobin variant, Hemoglobin A. This compound is critical for fundamental biochemical research and diagnostic development, serving as a key reference standard for studying oxygen transport and blood physiology. It is essential for researchers and manufacturers in the life sciences, clinical diagnostics, and pharmaceutical development sectors who require a well-characterized, high-purity biological standard.

Application

• Biochemical Research Standard: Used as a primary reference material for studying hemoglobin-oxygen binding kinetics, cooperativity, and allosteric effects.
• Clinical Diagnostics Calibration: Serves as a calibrant and control for advanced hematology analyzers and co-oximeters measuring oxygen saturation and hemoglobin derivatives.
• Pharmaceutical Development: Employed in the research and testing of blood substitutes, hemoglobin-based oxygen carriers (HBOCs), and therapeutic agents targeting blood disorders.
• Spectroscopic Studies: Acts as a standard for UV-Vis and other spectroscopic techniques due to its characteristic Soret band and visible absorption spectra.
• Educational & Reference Material: Supplied to academic and teaching institutions for laboratory instruction in biochemistry and physiology.
• Quality Control in Biotech: Used in the quality assurance processes for products and assays dependent on consistent hemoglobin performance.

Basic Information

Product Name	Oxyhemoglobin A
CAS No.	9062-91-3
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (tetramer)
Synonyms	HbO2 A; Oxyhaemoglobin A; Hemoglobin A (oxygenated); Human Adult Oxyhemoglobin; Hb A (Fe2+-O2); α2β2 Tetramer (oxygenated); Blood Hemoglobin A (oxygenated form); Methemoglobin-free Hemoglobin A
EINECS	Contact for details

Quality Control

Our Oxyhemoglobin A is produced and tested under stringent conditions to ensure high biological activity and purity, suitable for research and diagnostic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (by HPLC), methemoglobin content, and spectroscopic verification. We adhere to relevant quality management principles to ensure batch-to-batch consistency and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is sensitive to strong acids and organic solvents; ensure appropriate segregation in storage areas. Handle under conditions that minimize exposure to oxidizing agents.

Specification

Item	Specification
Appearance	Red, lyophilized powder or solution
Identification (UV-Vis)	Conforms to reference spectrum (Soret band ~415 nm, α/β bands ~541/577 nm)
Purity (HPLC)	≥ 95% (Hb A Tetramer)
Methemoglobin Content	≤ 3%
Protein Concentration	As specified on COA
Solvent/Buffer	Typically in phosphate buffer, pH ~7.4
Biological Activity (P50)	Contact for details
Endotoxin Level	< 1.0 EU/mg (upon request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.