Description

Gsk-3 Beta CAS NO 9059-09-0 is a highly specific and potent inhibitor of the Glycogen Synthase Kinase-3 beta enzyme, a critical regulator in numerous cellular signaling pathways. This compound is essential for researchers and developers in the life sciences sector, providing a precise tool for modulating key biological processes related to cell proliferation, metabolism, and differentiation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on areas such as oncology, neurodegenerative diseases, and metabolic disorders.

Application

• Pharmaceutical Research & Development: A key biochemical tool for studying and validating the role of GSK-3β in disease pathways, including Alzheimer's disease, diabetes, and cancer.
• Cell Signaling Pathway Analysis: Used to inhibit GSK-3β activity in cell-based assays to elucidate its function in Wnt/β-catenin, insulin, and other critical signaling cascades.
• Drug Discovery Screening: Serves as a reference standard and positive control in high-throughput screening (HTS) campaigns to identify novel GSK-3β inhibitors.
• Neurobiology Studies: Applied in research models to investigate tau protein phosphorylation and its implications in neurodegenerative conditions.
• Metabolic Disorder Research: Utilized to study the enzyme's role in glycogen synthesis and glucose homeostasis, relevant for type 2 diabetes research.
• Stem Cell Research: Employed to modulate GSK-3β to influence stem cell fate decisions, including self-renewal and differentiation.

Basic Information

Product Name	Gsk-3 Beta
CAS No.	9059-09-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GSK-3β Inhibitor; Glycogen Synthase Kinase-3 Beta Inhibitor; GSK-3β Inhibitor IX; GSK-3β Inhibitor 1; GSK3β Inhibitor; GSK3B Inhibitor; Kinase Inhibitor GSK-3β; CAS 9059-09-0
EINECS	Contact for details

Quality Control

Our Gsk-3 Beta is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation via advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.