Description

Pyrimidine-Nucleoside Phosphorylase is a crucial enzyme that catalyzes the reversible phosphorolysis of pyrimidine nucleosides, a fundamental reaction in nucleotide salvage pathways. This biocatalyst is essential for research and development in nucleoside chemistry, enabling the synthesis and modification of nucleoside analogs. It is primarily utilized by pharmaceutical researchers, biotech companies, and academic institutions focused on antiviral drug discovery, cancer therapeutics, and enzymatic synthesis platforms.

Application

• Enzymatic synthesis of pyrimidine nucleoside analogs for pharmaceutical research.
• Biocatalyst in the development of antiviral and anticancer prodrug activation systems.
• Key reagent in nucleotide salvage pathway studies and metabolic engineering.
• Tool enzyme for the preparation of radiolabeled or modified nucleosides.
• Component in diagnostic kits and assays for nucleoside metabolism.
• Use in biocatalytic processes for the green synthesis of high-value nucleosides.

Basic Information

Product Name	Pyrimidine-Nucleoside Phosphorylase
CAS No.	9055-35-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pyrimidine Nucleoside Phosphorylase; Uridine Phosphorylase (UP); Thymidine Phosphorylase (TP); PyNP; Nucleoside: orthophosphate ribosyltransferase; EC 2.4.2.2; Pyrimidine nucleoside: phosphate deoxyribosyltransferase; Pyrimidine phosphorylase
EINECS	Contact for details

Quality Control

Our enzyme products are manufactured and tested under stringent quality systems. Each batch is characterized for specific activity, purity, and stability to ensure consistent performance in research and process applications. A comprehensive Certificate of Analysis (COA) detailing activity units, protein content, and purity is provided with every shipment. Production can adhere to GMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is typically supplied as a lyophilized powder or in a buffered glycerol solution; refer to the specific COA for the recommended storage temperature and buffer conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or clear solution
Specific Activity	≥ XX units/mg protein
Protein Content (Biuret)	≥ XX %
Purity (SDS-PAGE)	≥ XX %
Identification (Activity)	Conforms
pH	XX - XX
Endotoxin (LAL)	< XX EU/mg
Storage Buffer	XX mM Tris-HCl, pH X.X

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.