Description

Ec 3.3.2.3 CAS NO 9048-63-9 is a high-purity enzyme preparation, specifically an epoxide hydrolase, used for the stereoselective hydrolysis of epoxides to their corresponding vicinal diols. This biocatalyst is critical for producing chiral intermediates with high enantiomeric purity, which are essential building blocks in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key biocatalyst for the enantioselective resolution of racemic epoxides to produce single-enantiomer diols for API manufacturing.
• Chiral Building Block Production: Enables the synthesis of optically pure vicinal diols used in complex molecule construction for drug discovery and development.
• Biocatalytic Process Development: Employed in green chemistry and enzymatic process optimization to replace traditional chemical hydrolysis methods.
• Fine Chemical Manufacturing: Used in the production of specialty chemicals, flavors, and fragrances requiring high stereochemical control.
• Metabolic Pathway Studies: A valuable tool in biochemical and pharmacological research for studying epoxide metabolism and detoxification pathways.
• Agrochemical Synthesis: Applied in the manufacture of chiral intermediates for herbicides, pesticides, and plant growth regulators.

Basic Information

Product Name	Ec 3.3.2.3
CAS No.	9048-63-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Epoxide Hydrolase; Epoxide Hydratase; EC 3.3.2.3; Arene Oxide Hydrolase; Microsomal Epoxide Hydrolase; mEH; HYL1; EPHX1; Xenobiotic Epoxide Hydrolase; Epoxide Hydrolyase
EINECS	Contact for details

Quality Control

Our Ec 3.3.2.3 enzyme preparation is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure high specific activity, purity, and stability, meeting the rigorous standards required for biocatalytic applications. Certificates of Analysis (COA) detailing activity units, protein content, and purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] U/mg protein
Protein Content (Bradford)	Reported on COA
Purity (SDS-PAGE)	≥ 90%
pH (for solutions)	7.0 - 7.5
Solvent (for solutions)	Specified buffer
Bioprocess Contaminants	Absence of specified host cell proteins/DNA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.