Description

Carboxypeptidase A CAS NO 11075-17-5 is a zinc-containing exopeptidase enzyme that catalyzes the hydrolysis of C-terminal amino acids from peptides and proteins. Its specificity for aromatic and branched-chain aliphatic residues makes it an indispensable tool for protein sequencing, structural analysis, and peptide synthesis. This high-purity enzyme is essential for research laboratories, diagnostic kit manufacturers, and biopharmaceutical companies engaged in proteomics and bioprocessing.

Application

• Protein Sequencing & Structural Analysis: Used to determine the C-terminal amino acid sequence of peptides and proteins, aiding in structural elucidation.
• Peptide Synthesis & Modification: Employed for the selective cleavage of terminal amino acids during the synthesis or modification of bioactive peptides.
• Proteomics Research: A critical reagent in mass spectrometry-based proteomic workflows for sample preparation and peptide mapping.
• Biopharmaceutical Processing: Utilized in the downstream processing of recombinant proteins to remove affinity tags or for controlled truncation.
• Diagnostic Assay Development: Incorporated into enzymatic assay kits for clinical diagnostics and biochemical research.
• Food Science & Enzymology Studies: Applied in research to study protein hydrolysis and enzyme kinetics.

Basic Information

Product Name	Carboxypeptidase A
CAS No.	11075-17-5
Molecular Formula	N/A (Protein)
Molecular Weight	~34.6 kDa (Approximate)
Synonyms	Carboxypeptidase A from Bovine Pancreas; Peptidyl-L-amino-acid hydrolase; CPA; Carboxypolypeptidase; 3.4.17.1; Pancreatic Carboxypeptidase A; Carboxypeptidase A1
EINECS	234-301-4

Quality Control

Our Carboxypeptidase A is manufactured under strict quality systems. Each lot is tested to ensure high specific activity, purity, and consistency suitable for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing assay, activity, purity by SDS-PAGE, and absence of contaminating protease activities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C. Reconstituted enzyme solutions should be aliquoted and stored at -20°C to avoid repeated freeze-thaw cycles. Keep the product under the recommended conditions to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Activity)	Conforms
Specific Activity	≥ 50 units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	≥ 80%
Loss on Drying	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.