Description

Chondro-6-Sulfatase From Proteus Vulgari S is a highly purified enzyme preparation derived from the *Proteus vulgaris* bacterium, specifically targeting the hydrolysis of the 6-sulfate group from chondroitin sulfate. This product is critical for research and industrial processes requiring the controlled degradation or structural analysis of glycosaminoglycans (GAGs). It is primarily utilized by biochemists, pharmaceutical researchers, and manufacturers in the life sciences sector for applications ranging from substrate preparation to the study of metabolic pathways.

Application

• Glycosaminoglycan (GAG) Research: Used for the specific desulfation of chondroitin-6-sulfate to study structure-activity relationships and biological functions.
• Pharmaceutical Intermediate Production: Acts as a biocatalyst in the synthesis or modification of heparin-like compounds and other sulfated polysaccharides for therapeutic development.
• Diagnostic Reagent Manufacturing: Incorporated into enzymatic assay kits for the detection and quantification of specific GAGs in clinical samples.
• Biochemical Substrate Preparation: Generates defined, desulfated chondroitin substrates for use in other enzymatic studies or as standards in analytical methods.
• Nutraceutical and Cosmetic Ingredient Processing: Employed to modify the molecular weight and bioactivity profile of chondroitin sulfate for enhanced bioavailability in supplements and skincare formulations.

Basic Information

Product Name	Chondro-6-Sulfatase From Proteus Vulgari S
CAS No.	9045-76-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chondroitin-6-sulfatase; Chondroitin sulfatase; Arylsulfatase B (related activity); Chondroitinase (ambiguous); Glycosaminoglycan 6-sulfatase; EC 3.1.6.-; Chondro-6-sulfatase; Bacterial chondroitin sulfatase
EINECS	Contact for details

Quality Control

Our Chondro-6-Sulfatase is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high enzymatic activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and absence of contaminating enzymatic activities. While not a compendial item, quality is assured against in-house specifications developed for research and industrial use. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and activity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Enzyme Activity)	Conforms
Specific Activity	> X units/mg protein (Contact for details)
Protein Content (Biuret)	> 90%
pH (in solution)	6.0 - 8.0
Contaminating Activities (e.g., Protease, other sulfatases)	Not detected

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.