Description

Antithrombin Iii CAS NO 9041-91-2 is a critical plasma-derived glycoprotein that acts as a major physiological inhibitor of thrombin and other serine proteases in the coagulation cascade. Its primary value lies in its essential regulatory function for maintaining normal hemostasis and preventing pathological thrombosis. This high-purity biological is indispensable for research, diagnostic, and therapeutic applications within the global biopharmaceutical and life science sectors.

Application

• Therapeutic Agent Production: As a key active pharmaceutical ingredient (API) in the manufacture of antithrombin III concentrates for treating hereditary or acquired deficiencies.
• Biochemical & Pharmaceutical Research: Used as a standard or reagent in studies of blood coagulation mechanisms, thrombosis, and hemostasis.
• Diagnostic Kit Manufacturing: Serves as a critical component in the calibration and production of clinical diagnostic assays for coagulation factor testing.
• Cell Culture & Biotechnology: Employed in specialized cell culture media and bioprocessing to control protease activity.
• Reference Standard: Acts as a high-purity reference material for quality control in pharmaceutical and diagnostic industries.

Basic Information

Product Name	Antithrombin Iii
CAS No.	9041-91-2
Molecular Formula	N/A (Protein)
Molecular Weight	~58 kDa
Synonyms	Antithrombin III; ATIII; AT 3; Serpin C1; Heparin Cofactor; Antithrombin; Antithrombin-3; AT-III; Antithrombin III Human; Antithrombin III (Human)
EINECS	Contact for details

Quality Control

Our Antithrombin III is manufactured and tested under strict quality systems to ensure it meets the rigorous standards required for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, activity, and safety profiles. We can supply material compliant with relevant pharmacopeial monographs (e.g., USP, EP) upon request, ensuring traceability, consistency, and regulatory support for our global partners.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Handle under appropriate conditions to maintain biological activity and purity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/Activity)	Conforms
Purity (SDS-PAGE)	≥ 95%
Specific Activity	Contact for details
Protein Content	By UV absorbance
Endotoxin	< 1.0 EU/mg
Residual Moisture (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.