Description

Urokinase CAS NO 9039-53-6 is a serine protease enzyme, also known as urokinase-type plasminogen activator (uPA), which plays a critical role in the fibrinolytic system by converting plasminogen to plasmin. This action is essential for the dissolution of blood clots, making it a vital therapeutic agent. It is primarily required by the pharmaceutical and biotechnology industries for the production of thrombolytic drugs, as well as for research applications in cell biology and oncology.

Application

• Thrombolytic Therapy: Active pharmaceutical ingredient (API) in medications for treating acute myocardial infarction, pulmonary embolism, and peripheral arterial occlusion.
• Biopharmaceutical Manufacturing: Used in the production and formulation of injectable clot-dissolving drugs.
• Cell Culture & Research: Employed in laboratory research to study cell migration, tissue remodeling, angiogenesis, and cancer metastasis due to its role in plasminogen activation.
• Diagnostic Reagents: A key component in in-vitro diagnostic kits for assessing fibrinolytic activity or related clinical parameters.
• Tissue Engineering: Applied in studies involving extracellular matrix degradation and remodeling.

Basic Information

Product Name	Urokinase
CAS No.	9039-53-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Urokinase-type plasminogen activator (uPA); Plasminogen activator, urokinase; EC 3.4.21.73; Uronase; Abbokinase; Win-Kinase; u-PA; UK
EINECS	Contact for details

Quality Control

Our Urokinase is produced and tested under strict quality management systems to ensure it meets the high standards required for pharmaceutical and research use. Each batch is subjected to comprehensive analytical testing, including potency, purity, and sterility assessments. Certificates of Analysis (COA) documenting compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept under controlled, dry conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder or lyophilized solid
Identification (IR)	Conforms to standard
Potency (Assay)	≥ 50,000 IU/mg (or as per grade)
Purity (HPLC)	≥ 95.0%
pH (Solution)	6.0 - 8.0
Loss on Drying	≤ 5.0%
Bacterial Endotoxins	< 1.0 EU/IU
Sterility	Sterile (or as per grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.