Description

Irisin (Human Recombinant) is a myokine, a hormone-like polypeptide produced by muscle tissue in response to exercise. This product is of significant interest for its role in metabolic regulation and potential therapeutic applications. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and biotechnology sectors for metabolic studies, drug discovery, and the development of diagnostic assays.

Application

• Biomedical Research: Used as a critical reagent in studies investigating the role of irisin in metabolism, energy homeostasis, and browning of white adipose tissue.
• Drug Discovery & Development: Serves as a reference standard and active pharmaceutical ingredient (API) in preclinical research for metabolic disorders such as obesity and type 2 diabetes.
• Diagnostic Kit Development: Employed as a calibrator or antigen in the development of immunoassays (e.g., ELISA) to measure irisin levels in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study its effects on cell signaling pathways, gene expression, and differentiation.
• Academic Research: Essential for universities and research institutions exploring exercise physiology, endocrinology, and metabolic health.

Basic Information

Product Name	Irisin (Human Recombinant)
CAS No.	9037-90-5
Molecular Formula	Contact for details
Molecular Weight	~12-25 kDa (glycosylated form)
Synonyms	FNDC5 Protein, Human; Fibronectin type III domain-containing protein 5; Exercise Hormone; Myokine Irisin; Recombinant Human FNDC5; Recombinant Human Irisin; irisin peptide
EINECS	Contact for details

Quality Control

Our Irisin (Human Recombinant) is produced under stringent conditions to ensure high purity and biological activity. Each batch undergoes rigorous quality testing, including analysis for identity, purity, potency, and endotoxin levels. Certificates of Analysis (COA) detailing specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to correct molecular weight
Purity (HPLC)	≥ 95%
Biological Activity (Cell-based assay)	Confirmed
Endotoxin Level (LAL)	< 1.0 EU/µg
Protein Content (UV)	≥ 80%
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.