Description

Blood-Coagulation Factor Xiii is a crucial enzyme in the final stage of the blood clotting cascade, responsible for cross-linking fibrin polymers to form a stable clot. This high-purity biological reagent is essential for research, diagnostic, and therapeutic applications where precise control of hemostasis is required. It is primarily utilized by biopharmaceutical manufacturers, clinical diagnostic laboratories, and advanced life science research institutions.

Application

• Biopharmaceutical Manufacturing: As a critical raw material or active ingredient in the production of hemostatic agents, fibrin sealants, and other plasma-derived therapeutics.
• Clinical Diagnostics: Used as a key component in coagulation factor assay kits and panels to diagnose congenital or acquired Factor XIII deficiencies.
• Biomedical Research: Fundamental research into blood coagulation mechanisms, thrombosis, wound healing, and the development of novel anti-thrombotic therapies.
• Quality Control & Standardization: Serving as a reference standard for calibrating diagnostic equipment and validating the potency of commercial Factor XIII products.
• Tissue Engineering: Investigation of its role in stabilizing fibrin-based scaffolds used for cell growth and tissue regeneration.

Basic Information

Product Name	Blood-Coagulation Factor Xiii
CAS No.	9035-67-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Factor XIII; Fibrin Stabilizing Factor; Fibrinoligase; Plasma Transglutaminase; Laki-Lorand Factor; FSF; F13A; Coagulation Factor XIII A Chain; Protein-glutamine γ-glutamyltransferase A chain; EC 2.3.2.13
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Manufacturing and release specifications are established to meet the stringent requirements for biological reagents. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, activity, and safety profiles. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under appropriate conditions to maintain stability and activity. For long-term storage, consider aliquoting and freezing at -20°C or below.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (IR / Electrophoresis)	Conforms to standard
Assay (Activity)	≥ 90% (by chromogenic or clotting assay)
Purity (SDS-PAGE / HPLC)	≥ 95%
Solubility	Clear, colorless solution in specified buffer
pH (in solution)	6.5 - 7.5
Endotoxin	< 1.0 EU/mg (for research grade)
Bioburden	To meet relevant pharmacopeial standards

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.