Description

Cytochrome B is a critical membrane-bound hemoprotein that functions as a core component of the mitochondrial electron transport chain, specifically within the bc1 complex (Complex III). Its primary commercial value lies in its essential role as a high-purity biochemical reagent for advanced life science research and diagnostic applications. This product is indispensable for researchers and manufacturers in the fields of molecular biology, enzymology, and biomedical diagnostics, where it is used to study cellular respiration, oxidative stress, and mitochondrial function.

Application

• Biochemical Research: As a key reagent for studying electron transfer mechanisms, mitochondrial dysfunction, and apoptosis.
• Enzyme Activity Assays: Used in spectrophotometric assays to measure the activity of cytochrome bc1 complex and related enzymes.
• Diagnostic Kit Manufacturing: Incorporated as a component in kits for research into metabolic disorders and cellular energy pathways.
• Pharmaceutical Development: Serves as a target or tool compound in drug discovery programs focused on diseases involving mitochondrial impairment.
• Academic & Industrial R&D: Fundamental protein for teaching and investigating principles of bioenergetics and membrane protein biochemistry.

Basic Information

Product Name	Cytochrome B
CAS No.	9035-37-4
Molecular Formula	Variable (Protein)
Molecular Weight	~42 kDa (Species-dependent)
Synonyms	Cytochrome b; Cytochrome b (mitochondrial); Complex III subunit cytochrome b; Ubiquinol-cytochrome-c reductase complex cytochrome b subunit; MT-CYB; COB; CYTB
EINECS	Contact for details

Quality Control

Our Cytochrome B is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for purity, identity, and functional integrity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Dark Brown to Red-Brown Lyophilized Powder
Identification (IR / UV-Vis)	Conforms to Standard
Purity (SDS-PAGE)	≥ 90%
Assay (Heme Content)	≥ 90% of theoretical
Specific Activity	Contact for details
Protein Content (Biuret)	≥ 95%
Solubility	Soluble in appropriate aqueous buffers
Endotoxin Level	< 1.0 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.