Description

Methyltransferase,Betaine-Homocysteine CAS NO 9029-78-1 is a critical enzyme that catalyzes the remethylation of homocysteine to methionine, a fundamental process in one-carbon metabolism. This enzymatic activity is essential for maintaining proper cellular function, gene regulation, and cardiovascular health. It is a vital reagent for biochemical research, pharmaceutical development, and diagnostic applications, particularly in studies related to epigenetics, metabolic disorders, and cardiovascular disease.

Application

• Biochemical Research: A key tool for studying methylation pathways, epigenetic regulation, and sulfur amino acid metabolism in vitro.
• Pharmaceutical Development: Used in drug discovery and screening for compounds targeting homocysteine metabolism and related cardiovascular or neurological conditions.
• Diagnostic Reagent Manufacturing: Incorporated into enzymatic assay kits for the quantitative measurement of homocysteine, betaine, or S-adenosylmethionine (SAM) levels in clinical and research laboratories.
• Enzymology Studies: Serves as a model enzyme for investigating enzyme kinetics, inhibition mechanisms, and cofactor dependencies.
• Nutritional & Metabolic Research: Employed to analyze the impact of nutrients like folate, vitamin B12, and betaine on the methionine cycle.

Basic Information

Product Name	Methyltransferase,Betaine-Homocysteine
CAS No.	9029-78-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Betaine-Homocysteine S-Methyltransferase; BHMT; Homocysteine S-Methyltransferase; EC 2.1.1.5; Betaine--Homocysteine Methyltransferase; Homocysteine Methyltransferase; Zinc-Binding Methyltransferase
EINECS	Contact for details

Quality Control

Our Methyltransferase,Betaine-Homocysteine is produced under stringent quality management systems. Each lot undergoes comprehensive analytical testing to ensure high specific activity, purity, and stability. Certificates of Analysis (COA) detailing assay results, protein concentration, and activity units are provided with every shipment to guarantee batch-to-batch consistency for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to prevent loss of activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	> X U/mg protein (Contact for details)
Purity (SDS-PAGE)	> 90%
Protein Concentration	Determined by UV or Bradford assay
Buffer Composition	Specified in COA
Stability	Stable under recommended storage conditions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.