Description

Aldehyde Dehydrogenase CAS NO 9028-86-8 is a critical oxidoreductase enzyme that catalyzes the NAD(P)+-dependent oxidation of aldehydes to their corresponding carboxylic acids. This enzymatic activity is fundamental in numerous metabolic pathways, making it an indispensable tool for biochemical research and industrial biocatalysis. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors who require precise and reliable enzymatic activity for metabolic studies, biosensor development, and fine chemical synthesis.

Application

• Biochemical Research & Metabolic Pathway Analysis: Used in vitro to study aldehyde metabolism, enzyme kinetics, and the role of ALDH in cellular processes.
• Diagnostic Kit Manufacturing: A key component in enzymatic assay kits for clinical diagnostics, particularly for measuring biomarkers related to alcohol metabolism and certain genetic disorders.
• Pharmaceutical Intermediate Synthesis: Employed as a biocatalyst in the stereoselective synthesis of chiral intermediates for active pharmaceutical ingredients (APIs).
• Biosensor Development: Integrated into electrochemical or optical biosensors for the detection of specific aldehydes, ethanol, or related metabolites.
• Toxicology and Detoxification Studies: Utilized to investigate the detoxification pathways of exogenous aldehydes and potential therapeutic targets.
• Food & Flavor Chemistry: Applied in enzymatic conversions for flavor enhancement or the modification of food components.

Basic Information

Product Name	Aldehyde Dehydrogenase
CAS No.	9028-86-8
Molecular Formula	N/A (Enzyme)
Molecular Weight	Varies by source and isoform
Synonyms	ALDH; Aldehyde Oxidoreductase; Aldehyde:NAD+ Oxidoreductase; Acylating Aldehyde Dehydrogenase; Aldehyde Dehydrogenase (NAD+); EC 1.2.1.3; EC 1.2.1.5
EINECS	Contact for details

Quality Control

Our Aldehyde Dehydrogenase is produced and tested under stringent quality management systems. Each lot is characterized for critical parameters including specific activity, protein content, and purity profile to ensure batch-to-batch consistency and performance reliability. Certificates of Analysis (COA) detailing assay results, stability data, and storage conditions are provided with every shipment. We support compliance with relevant cGMP and ISO 9001 standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into working portions after thawing to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
Identification (Activity)	Conforms
pH (in solution)	7.0 - 7.5
Solubility	Complete in buffer
Endotoxin (LAL)	< [Value] EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.