Description

Ec 3.5.4.4 is a high-purity enzyme preparation, specifically a nucleoside deaminase, identified by the CAS number 9026-93-1. This biocatalyst is essential for biochemical research and industrial processes requiring the specific deamination of nucleosides, such as adenosine. It is a critical reagent for pharmaceutical R&D, diagnostic kit manufacturing, and the synthesis of nucleoside analogs, where precise enzymatic activity and batch-to-batch consistency are paramount for reliable results and process scalability.

Application

• Pharmaceutical Research & Development: Used as a key enzyme in the study of nucleoside metabolism and for the synthesis of modified nucleosides with potential therapeutic applications.
• Diagnostic Kit Manufacturing: Serves as a critical component in enzymatic assays and diagnostic kits designed to measure adenosine or related metabolite levels in clinical samples.
• Biochemical Synthesis: Employed in the biocatalytic production of specific nucleoside intermediates for antiviral or anticancer drug candidates.
• Academic & Life Science Research: Utilized in university and institutional labs for fundamental studies in enzymology, molecular biology, and metabolic pathway analysis.
• Enzyme Engineering Studies: Acts as a model enzyme for protein engineering projects aimed at improving stability, substrate specificity, or catalytic efficiency.
• Food & Beverage Analysis: Potential use in analytical methods for detecting nucleotides or nucleosides in food products.

Basic Information

Product Name	Ec 3.5.4.4
CAS No.	9026-93-1
Molecular Formula	Protein (Enzyme)
Molecular Weight	Varies by preparation and source
Synonyms	Adenosine Deaminase; Adenosine Aminohydrolase; ADA; EC 3.5.4.4; Nucleoside Deaminase; Adenosine Deaminase (E.C. 3.5.4.4); 9026-93-1; Adenosine Deaminase from Bovine Spleen (common source)
EINECS	Contact for details

Quality Control

Our Ec 3.5.4.4 is produced and tested under stringent quality management systems. Each lot is characterized for critical parameters including specific activity, purity (via SDS-PAGE), and absence of contaminating nucleases. A comprehensive Certificate of Analysis (COA) detailing assay results, storage buffer, and unit definition is provided with every shipment to ensure it meets the rigorous demands of research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ XX units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	XX-XX mg/vial
pH (in solution)	7.0 - 7.5
Endotoxin (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.