Description

Ec 2.8.1.1 CAS NO 9026-04-4 is a high-purity enzyme preparation, specifically identified as Thiosulfate Sulfurtransferase (Rhodanese). This biocatalyst is essential for facilitating the transfer of a sulfur atom from thiosulfate to cyanide, forming thiocyanate, a critical detoxification pathway. It is a vital reagent for research and industrial applications in biochemistry, toxicology, and environmental science, where precise enzymatic activity is required.

Application

• Biochemical Research: Used as a model enzyme in studies of enzyme kinetics, sulfur metabolism, and detoxification mechanisms.
• Toxicology Assays: Employed in in vitro and in vivo studies to investigate cyanide detoxification and develop potential antidotes.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits for measuring sulfurtransferase activity or related metabolic functions.
• Environmental Science: Applied in research focused on microbial sulfur cycling and the biodegradation of sulfur-containing pollutants.
• Pharmaceutical Development: Investigated for its potential therapeutic applications in conditions related to abnormal sulfur metabolism or cyanide poisoning.
• Industrial Biocatalysis: Explored for use in specific biotransformation processes requiring sulfur transfer reactions.

Basic Information

Product Name	Ec 2.8.1.1 CAS NO 9026-04-4
CAS No.	9026-04-4
Molecular Formula	Protein (Enzyme)
Molecular Weight	~33 kDa (varies by source and isoform)
Synonyms	Thiosulfate Sulfurtransferase; Rhodanese; Thiosulfate Cyanide Transsulfurase; Thiosulfate-Thiocyanoate Sulfurtransferase; TST; EC 2.8.1.1; Rhodanase; Mitochondrial Rhodanese
EINECS	Contact for details

Quality Control

Our enzyme preparations are produced and tested under stringent quality management systems. Each batch is characterized for key parameters including specific activity, protein content, and purity (via SDS-PAGE). We ensure compliance with relevant research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing assay results, storage buffer, and activity units is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
Identification (Activity)	Conforms
pH (in solution)	6.0 - 8.0
Endotoxin (LAL)	< [Value] EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.