Description

Orotidine-5'-Monophosphate*Decarboxylase Purified Fr is a highly purified enzyme preparation, specifically the decarboxylase responsible for a critical step in pyrimidine nucleotide biosynthesis. This product is essential for biochemical research, diagnostic assay development, and enzymatic synthesis where precise catalytic activity is required. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on nucleotide metabolism, enzyme kinetics studies, and high-throughput screening applications.

Application

• Biochemical Research: Used as a key reagent in studies of the de novo pyrimidine biosynthesis pathway, enzyme mechanism, and inhibition kinetics.
• Diagnostic Kit Manufacturing: Serves as a critical component in enzymatic assays designed to measure orotidine-5'-monophosphate decarboxylase (OMP decarboxylase) activity in clinical samples.
• Pharmaceutical Development: Employed in target validation and high-throughput screening campaigns for identifying potential inhibitors as novel therapeutic agents.
• Enzymatic Synthesis: Facilitates the biocatalytic conversion of orotidine-5'-monophosphate (OMP) to uridine-5'-monophosphate (UMP) in controlled synthesis processes.
• Metabolic Pathway Analysis: A vital tool for in vitro reconstruction and analysis of nucleotide metabolic networks in cellular models.
• Quality Control Reference: Acts as a reference standard for activity assays in laboratories monitoring enzyme production or purification processes.

Basic Information

Product Name	Orotidine-5'-Monophosphate*Decarboxylase Purified Fr
CAS No.	9024-62-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	OMP Decarboxylase; Orotidine-5'-phosphate decarboxylase; Orotidylic acid decarboxylase; Orotidine monophosphate decarboxylase; EC 4.1.1.23; Orotidine-5'-P decarboxylase; UMP synthase (decarboxylase domain); ODCase
EINECS	Contact for details

Quality Control

Our Orotidine-5'-Monophosphate*Decarboxylase Purified Fr is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and functional consistency. A comprehensive Certificate of Analysis (COA) detailing activity units, protein concentration, purity assessment, and stability data is provided with every shipment to guarantee it meets the exacting standards required for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product should be handled under appropriate laboratory conditions to maintain enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Bradford)	Contact for details
Purity (SDS-PAGE)	≥ 90%
Identification (Activity)	Converts OMP to UMP
Buffer Composition	Contact for details
Stabilizers/Additives	None (or as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.