Description

Poly-(B-D-1,4-Mannuronide)-Lyase is a specialized enzyme that catalyzes the cleavage of glycosidic bonds in poly-mannuronate chains. This product is essential for the controlled depolymerization of alginate and related polysaccharides, enabling precise molecular weight control and the generation of bioactive oligosaccharides. It is a critical reagent for researchers and manufacturers in the biotechnology, pharmaceutical, and nutraceutical industries, particularly those developing advanced biomaterials, drug delivery systems, and functional food ingredients.

Application

• Alginate Oligosaccharide Production: For the enzymatic preparation of defined, low-molecular-weight mannuronate oligomers used in biomedical research and as bioactive compounds.
• Biomaterial Engineering: Modification of alginate-based hydrogels, scaffolds, and wound dressings to tailor their mechanical properties and degradation profiles.
• Pharmaceutical Research: Used in studies of carbohydrate-protein interactions, enzyme mechanisms, and the development of novel carbohydrate-based therapeutics.
• Food Science & Nutraceuticals: Generation of prebiotic oligosaccharides from algal sources for functional food and dietary supplement applications.
• Analytical Biochemistry: Serves as a specific tool for the structural analysis and sequencing of alginate polymers and related polysaccharides.
• Biofuel & Biorefinery Processes: Potential application in the enzymatic breakdown of algal biomass for sugar feedstock recovery.

Basic Information

Product Name	Poly-(B-D-1,4-Mannuronide)-Lyase
CAS No.	9024-15-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(β-D-1,4-mannuronide) lyase; Poly(mannuronate) lyase; Alginate lyase (EC 4.2.2.3); PolyM lyase; Mannuronan lyase; Poly-β-D-mannuronide lyase; Poly(1,4-α-L-guluronide) lyase (related activity); Alginate depolymerase
EINECS	Contact for details

Quality Control

Our Poly-(B-D-1,4-Mannuronide)-Lyase is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high specific activity, purity, and functional consistency. A comprehensive Certificate of Analysis (COA) detailing assay results, purity, and stability data is provided with every shipment to guarantee it meets your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which can affect enzymatic activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported
pH (in solution)	6.0 - 8.0
Endotoxin Level	< 1.0 EU/μg (for research-grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.