Description

Glycogen Synthase is a critical enzyme that catalyzes the rate-limiting step in the biosynthesis of glycogen, a primary energy storage polysaccharide in animals, fungi, and bacteria. Its function is essential for maintaining glucose homeostasis and energy balance in biological systems. This high-purity enzyme is indispensable for researchers in biochemistry, molecular biology, and pharmaceutical development, as well as for diagnostic kit manufacturers.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays to study glycogen metabolism, insulin signaling pathways, and enzyme kinetics.
• Pharmaceutical Development: Employed as a target enzyme in drug discovery programs for metabolic disorders such as diabetes and glycogen storage diseases.
• Diagnostic Manufacturing: Incorporated into in vitro diagnostic (IVD) kits for the quantitative measurement of enzyme activity in clinical samples.
• Enzyme Characterization: Serves as a standard for activity comparison, purity assessment, and structural studies in academic and industrial laboratories.
• Metabolic Pathway Analysis: A vital component in reconstituted systems for studying the regulation and integration of carbohydrate metabolism.

Basic Information

Product Name	Glycogen Synthase
CAS No.	9014-56-6
Molecular Formula	Protein (Enzyme)
Molecular Weight	Varies by source and isoform (typically ~80-90 kDa)
Synonyms	UDP-glucose-glycogen glucosyltransferase; Glycogen (starch) synthase; UDPG-glycogen transglucosylase; Glycogen-UDP glucosyltransferase; UDP-glucose:glycogen 4-α-glucosyltransferase; EC 2.4.1.11; GS; GYS
EINECS	Contact for details

Quality Control

Our Glycogen Synthase is produced under stringent conditions to ensure high specific activity and purity. Each lot undergoes comprehensive analytical testing, including activity assays, purity assessment by electrophoresis, and protein concentration determination. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous internal specifications suitable for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	> X units/mg protein (Lot-specific)
Purity (SDS-PAGE)	> 90%
Protein Content	Determined by UV or Bradford assay
Solubility	Reconstitutes clearly in suitable buffer
Stabilizers/Additives	May contain glycerol or buffer salts

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.