Description

Glutathione Peroxidase is a critical antioxidant enzyme that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides using reduced glutathione. This action is fundamental for protecting cells from oxidative damage and maintaining intracellular redox balance. It is an essential biochemical reagent and research tool for the pharmaceutical, nutraceutical, and life science research industries, particularly in studies related to oxidative stress, aging, and metabolic disorders.

Application

• Biochemical Research: A key reagent for studying oxidative stress pathways, antioxidant defense mechanisms, and free radical biology in cellular and animal models.
• Diagnostic Kit Manufacturing: Used as a core enzymatic component in clinical diagnostic assays and kits designed to measure oxidative stress markers or antioxidant capacity in biological samples.
• Pharmaceutical Development: Employed in drug discovery and development research targeting diseases associated with oxidative damage, such as neurodegenerative disorders, cardiovascular diseases, and cancer.
• Nutraceutical & Cosmetic Research: Serves as a reference standard and active ingredient research material for formulating antioxidant supplements and skincare products aimed at combating cellular aging.
• Enzymology Studies: Used to investigate enzyme kinetics, inhibition, and the structure-function relationships of selenium-dependent peroxidases.
• Food Science: Applied in research concerning the preservation of food quality and the study of natural antioxidant systems within food matrices.

Basic Information

Product Name	Glutathione Peroxidase
CAS No.	9013-66-5
Molecular Formula	N/A (Enzyme)
Molecular Weight	~85,000 Da (Tetramer, varies by source)
Synonyms	GPx; Glutathione Peroxidase (GPX1); Glutathione-Hydrogen-Peroxide Oxidoreductase; EC 1.11.1.9; Selenium-dependent glutathione peroxidase; Cellular glutathione peroxidase; Erythrocyte glutathione peroxidase
EINECS	Contact for details

Quality Control

Our Glutathione Peroxidase is produced and tested under stringent quality management protocols. Each lot is characterized for specific activity, purity, and stability to ensure it meets the exacting requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA), detailing activity units (U/mg), protein content, and purity assessments, is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture absorption. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ 100 units/mg protein
Protein Content (Biuret)	Contact for details
Purity (SDS-PAGE)	≥ 90%
Solubility	Soluble in water or specified buffer
Stability	Stable for 24 months at -20°C when stored as directed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.