Description

Apoferritin is the iron-free protein shell of the ferritin complex, a critical biomolecule for iron storage and metabolism. This high-purity protein is essential for research and development in biochemistry, nanotechnology, and diagnostics, where a precisely defined, iron-free scaffold is required. It is particularly valuable for scientists and manufacturers in the pharmaceutical, biomedical research, and advanced materials sectors who require a consistent and reliable protein substrate.

Application

• Biomedical Research: Used as a model protein for studying iron metabolism, protein cage assembly, and as a template for nanoparticle synthesis.
• Nanotechnology & Drug Delivery: Serves as a biocompatible nanocage for encapsulating and delivering therapeutic agents, imaging probes, or catalysts.
• Diagnostic Reagent Production: Employed in the development of immunoassays and as a carrier protein for haptens in antibody production.
• Bioconjugation & Labeling Studies: Provides a well-characterized protein surface for studying chemical modification, cross-linking, and fluorescent labeling techniques.
• Reference Standard: Acts as a critical standard in analytical laboratories for calibrating instruments and validating methods related to ferritin analysis.
• Materials Science: Utilized as a building block for creating ordered protein arrays and bio-inspired inorganic-organic hybrid materials.

Basic Information

Item	Detail
Product Name	Apoferritin
CAS No.	9013-31-4
Molecular Formula	Protein (Complex)
Molecular Weight	~440 kDa (Variable by source)
Synonyms	Iron-free Ferritin; Ferritin Apo-Protein; Native Apoferritin; Horse Spleen Apoferritin (common source); Protein Cage; Ferritin Light Chain (in context); Ferritin Heavy Chain (in context); Ft-L (abbreviation)
EINECS	Contact for details

Quality Control

Our Apoferritin is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity, iron content, and oligomeric state. We adhere to relevant guidelines for research-grade biological products to support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C. Reconstituted solutions should be aliquoted and stored at 2-8°C for short-term use or at -20°C to -80°C for extended storage. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to standard
Purity (HPLC)	≥ 95% (Protein basis)
Iron Content (AAS/ICP-MS)	< 5 atoms per protein molecule
Protein Concentration (UV)	As per COA
Oligomeric State (SEC)	Predominantly 24-mer
Biological Activity	Capable of reconstitution with iron
Endotoxin (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.