Description

Actomyosin is a vital protein complex fundamental to muscle contraction and cellular motility, formed from the interaction of actin and myosin. This biochemical workhorse is essential for research into muscle physiology, cytoskeletal dynamics, and the molecular mechanisms of movement. It serves as a critical reagent for biochemists, pharmaceutical researchers, and diagnostic developers working in life sciences, drug discovery, and biomedical diagnostics.

Application

• Biochemical & Physiological Research: Used as a standard substrate for studying the mechanics of muscle contraction, ATP hydrolysis, and the regulation of the actomyosin cycle.
• In Vitro Motility Assays: Essential for reconstituting and visualizing filament sliding on myosin-coated surfaces to study motor protein function and kinetics.
• Pharmaceutical Screening: Employed in target-based assays to identify and characterize novel compounds that modulate actomyosin activity for potential therapeutic applications.
• Diagnostic Kit Development: Acts as a key component in the development of immunoassays and other diagnostic tests related to muscle disorders and autoimmune diseases.
• Food Science Research: Utilized in studying the textural and functional properties of muscle proteins in meat and seafood products.
• Educational & Teaching Tools: Serves as a demonstration material for advanced biology and biochemistry courses on cell motility and muscle biology.

Basic Information

Product Name	Actomyosin
CAS No.	9013-26-7
Molecular Formula	Protein Complex
Molecular Weight	Variable (High Molecular Weight Complex)
Synonyms	Actin-Myosin Complex; Myosin B; Natural Actomyosin; Muscle Contractile Protein; Actomyosin ATPase; ATPase, Actomyosin; Myosin-actin complex
EINECS	Contact for details

Quality Control

Our Actomyosin is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous quality testing, including assessment of purity, ATPase activity, and functional integrity in motility assays. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or suspension
Identification (Functional Assay)	Positive for ATP-dependent motility/superprecipitation
Protein Content (Biuret/Bradford)	≥ 90%
ATPase Activity	Specified range per batch (COA)
Solubility	Soluble in appropriate low-ionic-strength buffers
Biological Activity	Confirmed by in vitro motility assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.