Description

Choline Acetyltransferase Fromhuman Plac Enta is a purified enzyme preparation derived from human placental tissue, identified by CAS No. 9012-78-6. This enzyme is critical for catalyzing the biosynthesis of the essential neurotransmitter acetylcholine, making it a vital reagent for neurological and biochemical research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on neurochemistry, cholinergic system studies, and enzyme activity assays.

Application

• Biochemical Research: Essential for in vitro studies of acetylcholine synthesis, cholinergic neurotransmission, and enzyme kinetics.
• Pharmaceutical Development: Used in drug discovery platforms targeting neurodegenerative diseases (e.g., Alzheimer's, Parkinson's) and myasthenia gravis.
• Diagnostic Manufacturing: Serves as a key component in enzymatic assay kits for clinical and research laboratories to measure choline acetyltransferase activity.
• Neurotoxicology Studies: Employed to assess the effects of toxins, pesticides, or novel compounds on the cholinergic system.
• Academic & Clinical Research: Supports fundamental neuroscience research into synaptic function, memory, and learning mechanisms.

Basic Information

Item	Detail
Product Name	Choline Acetyltransferase Fromhuman Plac Enta
CAS No.	9012-78-6
Molecular Formula	Protein (Enzyme)
Molecular Weight	Approx. 68-72 kDa (Contact for details)
Synonyms	Choline Acetyltransferase; ChAT; Acetyl-CoA:choline O-acetyltransferase; EC 2.3.1.6; Choline O-acetyltransferase; Human Placental ChAT; Choline Acetylase
EINECS	Contact for details

Quality Control

Our Choline Acetyltransferase is produced and handled under controlled conditions to ensure high biological activity and purity. Each lot undergoes rigorous quality testing, including activity assays and purity assessments. A comprehensive Certificate of Analysis (COA) detailing specific activity, protein content, and stability is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	> 0.1 unit/mg protein (Contact for details)
Purity (SDS-PAGE)	> 90%
Protein Content	Determined by Bradford or similar method
Stabilizers/Buffers	May contain glycerol or buffer salts
Biological Activity	Confirmed by standard enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.