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3β-[3-o-Methyl-4-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-2,6-Dideoxy-β-D-Ribo-Hexopyranosyloxy]-14-Hydroxy-5β-Cardanolide-20(22)-Ene CAS NO 9007-56-1
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CAS No.:9007-56-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[3-o-Methyl-4-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-2,6-Dideoxy-β-D-Ribo-Hexopyranosyloxy]-14-Hydroxy-5β-Cardanolide-20(22)-Ene is a complex cardenolide glycoside, a class of compounds known for their potent biological activity. This high-purity compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of cardiac glycosides and their mechanisms. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector. Its precise structure makes it essential for analytical method development, bioactivity screening, and the synthesis of novel therapeutic agents.
Application
- Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control, method validation, and regulatory submissions in drug development.
- Cardiac Drug Research: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the research and synthesis of novel cardiotonic agents.
- Biochemical Research: Employed in pharmacological studies to investigate the structure-activity relationships (SAR) of cardenolide glycosides and their interaction with biological targets like Na+/K+-ATPase.
- Analytical Chemistry: Essential for developing and calibrating analytical methods such as HPLC, LC-MS, and NMR for the quantification of cardenolides in complex matrices.
- Natural Product Isolation & Standardization: Acts as a benchmark for the identification and quantification of similar glycosides in plant extracts and herbal formulations.
Basic Information
| Product Name | 3β-[3-o-Methyl-4-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-2,6-Dideoxy-β-D-Ribo-Hexopyranosyloxy]-14-Hydroxy-5β-Cardanolide-20(22)-Ene |
| CAS No. | 9007-56-1 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Gitoxin; Bigitalin; Anhydrogitalin; 16-Formylgitoxigenin 3-O-[O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranoside]; 3β-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Digitalis glycoside |
| EINECS | Contact for details |
Quality Control
Our 3β-[3-o-Methyl-4-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-2,6-Dideoxy-β-D-Ribo-Hexopyranosyloxy]-14-Hydroxy-5β-Cardanolide-20(22)-Ene is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific pharmacopeial or internal specifications upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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