Description

Uricase CAS NO 9002-12-4 is a highly specific enzyme that catalyzes the oxidation of uric acid to allantoin, a more soluble and easily excreted compound. This catalytic action is critical for applications requiring precise uric acid quantification or degradation. It is an essential reagent for manufacturers and research institutions in the in-vitro diagnostic (IVD), pharmaceutical, and biochemical research sectors.

Application

• Clinical Diagnostics: Key component in enzymatic assay kits for the quantitative determination of uric acid in human serum, plasma, and urine, aiding in the diagnosis and management of gout, kidney disorders, and metabolic syndrome.
• Biopharmaceutical Production: Used in the development of therapeutic enzymes (e.g., pegloticase) for the treatment of chronic gout in patients refractory to conventional therapy.
• Food & Beverage Analysis: Employed in enzymatic methods to measure uric acid content in food products and beverages for quality control and nutritional labeling.
• Biochemical Research: Serves as a vital tool in metabolic pathway studies, oxidative stress research, and enzymatic reaction modeling in academic and industrial R&D laboratories.
• Veterinary Diagnostics: Utilized in test kits for monitoring uric acid levels in avian and reptilian species, where it is the primary end product of nitrogen metabolism.

Basic Information

Product Name	Uricase
CAS No.	9002-12-4
Molecular Formula	N/A (Protein)
Molecular Weight	Approx. 32-34 kDa (subunit) / ~130 kDa (tetramer) - Contact for details
Synonyms	Urate Oxidase
Uric Acid Oxidase
Uricase (Aspergillus flavus)
EC 1.7.3.3
Urate:oxygen oxidoreductase
Rasburicase (recombinant form)
Pegloticase (PEGylated form)
EINECS	232-656-0

Quality Control

Our Uricase is produced and tested under a rigorous quality management system. Each batch is characterized for critical parameters including specific activity, purity, and stability to ensure performance consistency for diagnostic and research applications. Certificates of Analysis (COA) detailing assay results, protein content, and activity units are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / Activity)	Conforms
Specific Activity	> 5 U/mg protein
Protein Content (Biuret)	> 90%
Purity (SDS-PAGE)	> 95%
pH (in solution)	7.0 - 9.0
Loss on Drying	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.