Description

Streptokinase CAS NO 9002-01-1 is a highly purified, potent fibrinolytic enzyme derived from β-hemolytic streptococci. This thrombolytic agent is critical for the rapid dissolution of pathological blood clots, restoring blood flow and preventing tissue damage. It is an essential active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical and biotechnology sectors, primarily used in life-saving cardiovascular and thromboembolic therapies.

Application

• Thrombolytic Drug Formulation: Primary API in injectable formulations for the emergency treatment of acute myocardial infarction (heart attack), pulmonary embolism, and deep vein thrombosis (DVT).
• Cardiovascular Research: Used as a standard tool in biochemical and pharmacological research to study fibrinolysis, clot dissolution mechanisms, and to develop new antithrombotic agents.
• Diagnostic Reagents: A key component in in vitro diagnostic kits for assessing fibrinolytic activity and plasma clot lysis time in clinical laboratories.
• Biotechnological Processes: Employed in enzymatic debridement and in specific bioprocessing applications where targeted proteolytic activity is required.
• Veterinary Medicine: Formulated for thrombolytic therapy in companion and livestock animals for similar cardiovascular conditions.

Basic Information

Product Name	Streptokinase
CAS No.	9002-01-1
Molecular Formula	N/A (Protein)
Molecular Weight	~47 kDa (Monomer)
Synonyms	Streptococcal fibrinolysin; Plasminokinase; SK; Kabikinase (trade name); Streptase (trade name); Staphylokinase (related); Fibrinolytic enzyme from Streptococcus
EINECS	Contact for details

Quality Control

Our Streptokinase is manufactured under strict quality management systems. Each batch is subjected to a comprehensive battery of tests including potency (IU/mg) assay, purity analysis by HPLC, sterility testing, endotoxin limits (LAL), and identity confirmation. We provide full traceability and Certificates of Analysis (COA) that detail compliance with relevant pharmacopoeial standards, ensuring it meets the rigorous requirements for pharmaceutical ingredient use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (IR)	Conforms
Potency	≥ 100,000 IU/mg
Purity (HPLC)	≥ 95.0%
pH (Solution)	6.5 - 7.5
Loss on Drying	≤ 5.0%
Bacterial Endotoxins	< 10 EU/mg
Sterility	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.