Description

Plasmin CAS NO 9001-90-5 is a proteolytic enzyme derived from bovine plasma or through recombinant technology, functioning as a key serine protease in the fibrinolytic system. This enzyme is critical for its ability to degrade fibrin clots, making it an essential research and diagnostic tool in the life sciences. It is primarily utilized by biotechnology companies, pharmaceutical R&D laboratories, and diagnostic manufacturers for applications in thrombolytic research, cell culture, and biochemical assays.

Application

• Thrombolytic & Fibrinolytic Research: Used as a model enzyme to study clot dissolution mechanisms and to screen potential therapeutic agents.
• Cell Culture & Tissue Engineering: Employed for the detachment of adherent cell lines and the digestion of extracellular matrix proteins.
• Diagnostic Reagent Manufacturing: A key component in the production of in-vitro diagnostic kits for coagulation and fibrinolysis testing.
• Biochemical Assay Development: Serves as a substrate-specific protease in enzymatic activity assays and protein interaction studies.
• Pharmaceutical Processing: Used in downstream purification processes for the cleavage of fusion tags from recombinant proteins.

Basic Information

Product Name	Plasmin
CAS No.	9001-90-5
Molecular Formula	N/A (Protein)
Molecular Weight	~88 kDa (Approximate)
Synonyms	Fibrinolysin; Plasmin Human; Plasmin from Human Plasma; Plasmin, Bovine; EC 3.4.21.7; Serum Tryptase; Actase; Thrombolysin
EINECS	232-648-5

Quality Control

Our Plasmin is manufactured under strict quality systems. Each lot undergoes rigorous testing to ensure high purity, specific activity, and the absence of contaminating proteases. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for activity (IU/mg), purity (by SDS-PAGE and HPLC), and endotoxin levels. Production adheres to relevant quality guidelines suitable for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to prevent autolysis and loss of activity. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms (Chromogenic substrate assay)
Specific Activity	≥ 10 IU/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	Contact for details
Solubility	Clear, colorless solution in specified buffer
Endotoxin (LAL)	< 1.0 EU/μg
Residual Moisture (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.