Description

Phosphorylase Kinase is a crucial regulatory enzyme that plays a central role in glycogen metabolism by catalyzing the phosphorylation and activation of glycogen phosphorylase. This product is essential for researchers and manufacturers studying cellular energy regulation, signal transduction pathways, and metabolic disorders. It is primarily utilized in biochemical research, diagnostic assay development, and pharmaceutical discovery within the life sciences and biotechnology sectors.

Application

• Biochemical Research: A key reagent for in vitro studies of glycogen metabolism, enzyme kinetics, and phosphorylation cascades.
• Diagnostic Development: Used in the development of enzyme-linked assays and test kits for metabolic disease research.
• Pharmaceutical Screening: Employed as a target enzyme in high-throughput screening for potential modulators of glycogen metabolism.
• Enzymology Studies: Essential for investigating allosteric regulation, calcium/calmodulin dependence, and the structure-function relationship of serine/threonine kinases.
• Educational & Reference Standard: Serves as a purified enzyme standard for academic teaching and quality control in related bioprocesses.

Basic Information

Product Name	Phosphorylase Kinase
CAS No.	9001-88-1
Molecular Formula	Contact for details
Molecular Weight	~1.3 MDa (Complex, varies by source and subunit composition)
Synonyms	PhK; Phosphorylase b Kinase; Glycogen Phosphorylase Kinase; ATP:phosphorylase-b phosphotransferase; 1,4-α-Glucan Phosphorylase Kinase; Phosphorylase Phosphokinase; Phosphorylase Activating Kinase
EINECS	Contact for details

Quality Control

Our Phosphorylase Kinase is produced and tested under stringent conditions to ensure high activity, purity, and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specific activity, purity assessments, and functional performance data. We adhere to relevant quality management standards to support research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under anhydrous conditions after each use.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	> X units/mg protein (Lot-specific)
Purity (SDS-PAGE)	> 90%
Protein Content (Bradford)	Reported per COA
Buffer Composition	Reported per COA
Endotoxin Level (LAL)	< 1.0 EU/μg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.