Description

Phospholipase A2 (PLA2) is a critical hydrolytic enzyme that catalyzes the cleavage of fatty acids from the sn-2 position of phospholipids. This specific action makes it an indispensable biocatalyst for modifying lipid structures and generating bioactive lysophospholipids and free fatty acids. It is essential for industries requiring precise lipid engineering, such as pharmaceutical development, food ingredient manufacturing, and biochemical research.

Application

• Pharmaceutical Intermediates: Synthesis of lysophospholipids and other bioactive lipid molecules for drug delivery systems and active pharmaceutical ingredients (APIs).
• Food Processing & Ingredient Modification: Used in the dairy industry for cheese flavor enhancement, in baking for dough conditioning, and for the production of emulsifiers like lysolecithin.
• Diagnostic Reagents: A key component in clinical diagnostic kits for the enzymatic determination of phospholipids and related biomarkers.
• Biochemical Research & Cell Biology: Essential tool for studying cell membrane structure, signal transduction pathways involving lipid mediators, and apoptosis.
• Oil & Fat Refining: Employed in the degumming of vegetable oils to remove phospholipids, improving oil stability and refining efficiency.
• Cosmetic Formulations: Used to create skin-compatible lipid ingredients with specific emulsifying or bioactive properties.

Basic Information

Product Name	Phospholipase A2
CAS No.	9001-84-7
Molecular Formula	N/A (Enzyme)
Molecular Weight	Approx. 13-15 kDa (Varies by source)
Synonyms	Phosphatidylcholine 2-acylhydrolase; Lecithinase A; PLA2; Phospholipase A; 1-Acyl-2-lysophosphatidylcholine acylhydrolase; EC 3.1.1.4; Phosphatidolipase
EINECS	232-631-6

Quality Control

Our Phospholipase A2 is produced and tested under a rigorous quality management system. Each batch is characterized for key enzymatic parameters to ensure consistent activity and purity, meeting the requirements for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing specific activity, protein content, and purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	> 500 units/mg protein
Protein Content (Biuret)	> 90%
Identification (IR)	Conforms
pH (in solution)	6.0 - 8.0
Loss on Drying	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.